| Date | Player | Strikeouts | |
| 05/11/1998 | Leonardo Flores | 15 K, 2 BB and 8.0 IP versus Potosi while playing for Rochester | |
| 07/13/2009 | Eric Spears | 16 K, 0 BB and 8.1 IP versus Washington while playing for Lubbock | |
| 08/06/2010 | Juan Betancourt | 15 K, 2 BB and 8.2 IP versus Hampton Manor while playing for Modesto | |
| 05/08/2014 | Giancarlo Madonia | 16 K, 0 BB and 9.0 IP versus Birmingham while playing for Potosi | |
| 08/09/2014 | Santiago Hernández | 16 K, 1 BB and 9.0 IP versus Vancouver while playing for Potosi | |
| 06/06/2015 | Daniel Moore | 15 K, 1 BB and 8.0 IP versus Lake Placid while playing for Washington | |
| 06/05/2016 | Adam Rogers | 16 K, 0 BB and 8.1 IP versus Rhinelander while playing for Chandler | |
| 07/08/2017 | Guillermo Delgado | 15 K, 3 BB and 9.0 IP versus Erlanger while playing for Colorado Springs | |
| 04/12/2022 | Anthony Ward | 15 K, 2 BB and 8.0 IP versus Lubbock while playing for Medicine Hat | |
| 05/21/2022 | Vincente González | 15 K, 3 BB and 8.0 IP versus Orinda while playing for Lake Placid | |
| 07/10/2022 | Fred Daniels | 15 K, 1 BB and 7.1 IP versus Colorado Springs while playing for Birmingham | |
| 05/24/2023 | Nate Bingham | 17 K, 0 BB and 8.0 IP versus Bakersfield while playing for Birmingham | |
| 08/07/2023 | John Ellison | 16 K, 0 BB and 9.0 IP versus Hampton Manor while playing for Chandler | |
| 05/16/2025 | Frederick Erickson | 15 K, 0 BB and 9.0 IP versus Washington while playing for Modesto | |
